Group Leaders: Professor Russell Dale and Dr Fabienne Brilot-Turville
Our research indicates autoantibodies are playing a significant role in neurological diseases, including autoimmune encephalitis, demyelinating syndromes, movement disorders and early-onset psychosis. These investigations are providing a better understanding of the biology of neurological and psychiatric diseases, improving diagnosis and pointing to novel treatment approaches for children with these debilitating illnesses.
Current projects include:
- Antibodies associated with demyelination in childhood multiple sclerosis
- Diagnosis and treatment of epilepsy caused by autoimmune disorders
- Dopamine-2 receptor antibody in movement and psychiatric disorders
- An autoimmune model of NMDAR encephalitis in children
- MOG antibody: a biomarker of demyelinating disorders