Key Publications

Bradbury PM, Turner K, Mitchell C, Griffin KR, Middlemiss S, Lau L, Dagg R, Taran E, Cooper-White J, Fabry B, O'Neill GM. The focal adhesion targeting domain of p130Cas confers a mechanosensing function. J Cell Sci. 2017 130(7):1263-1273.

Mitchell CB, O'Neill GM. Cooperative cell invasion: matrix metalloproteinase-mediated incorporation between cells. Mol Biol Cell. 2016 27(21):3284-3292

Grundy TJ, De Leon E, Griffin KR, Stringer BW, Day BW, Fabry B, Cooper-White J, O'Neill GM. Differential response of patient-derived primary glioblastomacells to environmental stiffness. Sci Rep. 2016 Mar 21;6:23353.

Bach CT, Murray RZ, Owen D, Gaus K, O'Neill GM. Tropomyosin Tm5NM1 spatially restricts src kinase activity through perturbation of Rab11 vesicle trafficking. Mol Cell Biol. 2014 34(24):4436-46.

Bradbury P, Bach CT, Paul A, O'Neill GM. Src kinase determines the dynamic exchange of the docking protein NEDD9 (neural precursor cell expressed developmentally down-regulated gene 9) at focal adhesions. J Biol Chem. 2014 289(36):24792-800.

Zhong J, Baquiran JB, Bonakdar N, Lees J, Ching YW, Pugacheva E, Fabry B, O'Neill GM. NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PLoS One. 2012;7(4):e35058.

Lees JG, Bach CT, Bradbury P, Paul A, Gunning PW, O'Neill GM. The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility. Oncogene. 2011 30(10):1241-51.

Bach CT, Creed S, Zhong J, Mahmassani M, Schevzov G, Stehn J, Cowell LN, Naumanen P, Lappalainen P, Gunning PW, O'Neill GM. Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol. 2009 29(6):1506-14.

A full list of publications can be found here