Key Publications

Lee JG, Gorgani NN, Ammit AJ, McCluskey A, Robinson PJ, O'Neill GM (2015) Role of dynamin in elongated cell migration in a 3D matrix. BBA Mol Cell Res 1854(3):611-618

Cheung BB, Tan O, Koach J, Liu B, Shum MS, Carter DR, Sutton S, Po'Uha ST, Chesler L, Haber M, Norrois MD, Kavallaris M, Liu T, O'Neill GM, Marshall GM (2015) Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma. Mol Oncol [Epub ahead of print]

Bach CT, Murray RZ, Owen D, Gaus K, O’Neill GM (2014) Tropomyosin Tm5NM1 spatially restricts Src kinase activity through perturbation of Rab11 vesicle trafficking. Molecular and Cellular Biology 34: 4436-4446

Bradbury P, Bach C, Paul A, O'Neill GM (2014) Src Kinase Determines the Dynamic Exchange of the Docking Protein Neural precursor cell Expressed Developmentally Down-regulated gene 9 (NEDD9) at Focal Adhesions. The Journal of Biological Chemistry 289(36): 24792-24800

Zhong Z, Bach C, Shum M, O'Neill GM (2014) NEDD9 Regulates 3D Migratory Activity Independent of the Rac1 Morphology Switch in Glioma and Neuroblastoma. Molecular Cancer Research 12(2): 264-273

Lees JG, Ching YW, Adams DH, Bach CT, Samuel MS, Kee AJ, Hardeman EC, Gunning P, Cowin AJ, O'Neill GM (2013) Tropomyosin regulates cell migration during skin wound healing. J Invest Dermatol 133(5):1330-1339

Zhong J, Baquiran JB, Bonakdar N, Lees J, Ching YW, Pugacheva E, Fabry B and O’Neill GM (2012) NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially affects 2D versus 3D cell migration. PLoS ONE 7(4):e35058

Lees JG, Bach CTT, Bradbury P, Paul A, Gunning PW and O’Neill GM (2011) The actin-associating protein Tm5NM1 blocks mesenchymal motility without transition to amoeboid motility. Oncogene 30(10):1241-1251