Key Publications

Clinical Trial of MGMT(P140K) Gene Therapy in the Treatment of Pediatric Patients with Brain Tumors. Kramer B, Singh R, Wischusen J, Rush A, Middlemiss S, Ching YW, Alexander IE, McCowage G. (2018) Human Gene Therapy. (Ahead of print)

Coherence analysis discriminates between retroviral integration patterns in CD34(+) cells transduced under differing clinical trial conditions. Hallwirth CV, Garg G, Peters TJ, Kramer BA, Malani NV, Hyman J, Ruan X, Ginn SL, Hetherington NA, Veeravalli L, Shahab A, Ranganathan S, Wei CL, Liddle C, Thrasher AJ, Bushman FD, Buckley MJ, Alexander IE (2015) Mol Ther Methods Clin Dev 2:15015

Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukemia. Milne E, Greenop KR, Scott RJ, Haber M, Norris MD, Attia J, Jamieson SE, Miller M, Bower C, Bailey HD, Dawson S, McCowage GB, et al. (2015) Cancer Epidemiol Biomarkers Prev 24(1):48-56

Treatment of children with poor risk solid tumors by further escalation of the VETOPEC regimen including very high-dose cyclophosphamide and peripheral stem cell support: an Australian and New Zealand Children's Hematology and Oncology Group study. McCowage GB, et al; Australian and New Zealand Children's Haematology and Oncology Group (ANZCHOG) (2011) Pediatr Blood Cancer 2011 57(6):958-64

Methylguanine DNA methyltransferase-mediated drug resistance-based selective enrichment and engraftment of transplanted stem cells in skeletal muscle. Lee AS, Kahatapitiya P, Kramer B, Joya JE, Hook J, Liu R, Schevzov G, Alexander IE, McCowage G, et al. (2009) Stem Cells 27(5):1098-108

Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow. Kramer BA, Lemckert FA, Alexander IE, Gunning PW, McCowage GB (2006) J Gene Med 8(9):1071-85