Recent key publications - Focal Adhesion Biology in Cancer Group

For a full list of publications by GM O'Neill, please visit http://www.ncbi.nlm.nih.gov/sites/entrez and use the following search:
"O'Neill GM OR (O'Neill G and Gunning P) OR (Singh M and Cowell L) NOT Karras D NOT Chishti AH"

Gunning PW and O'Neill GM (2005). The Cas family docking molecule, HEF1, promotes the formation of neurite-like membrane extensions. BBA Mol. Cell Res. 1746; 143-154

Cowell LN, Graham JD, Bouton A, Clarke CL and O'Neill GM (2006). Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway. Oncogene. 25; 7597-7607

Singh MK, Cowell LN, Seo S, O'Neill GM and Golemis EA. (2007). Molecular basis for HEF1/NEDD9/CAS-L action as a central coordinator in migration, apoptosis and cell-cycle. Cell Biochem. Biophys. 48; 54-72

O'Neill GM, Seo S, Serebriiskii IG, Lessin S and Golemis EA. (2007) A new central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9. Cancer Res. 67; 1 - 4

O'Neill GM, Stehn J and Gunning PW. (2008) Tropomyosins as interpreters of the signalling environment to regulate the local cytoskeleton. Sem. Cancer Biol. 18; 35-44

Bach CT, Creed S, Zhong J, Mahmassani M, Schevzov G, Stehn J, Cowell LN, Naumanen P, Lappalainen P, Gunning PW, O'Neill GM. (2009) Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol. Mar;29(6):1506-14.