Virology Research Group
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The Virology Research Group aims to increase understanding of the basic biology of viral infections in children – how viruses interact with cells and how they evade the body's immune response.
There are two core areas of research: how the Flavivirus affects the regulation of immune cells, and the role of viruses in childhood diarrhoeal illnesses.
The Virology Research Group has recently defined two pathways for up-regulation of immune recognition molecules in mammalian cells. This work will inform understanding of immunity and assist with understanding vaccination risks.
The group is also collaborating with a mathematician to model the survival impact on the host of the alteration in the level of expression of immune recognition molecules.
Its work on the prevalence of rotavirus, norovirus and astrovirus among Australian children and a study of the genotypes that occur in our population will have implication for the future design of vaccines against these viruses.