Recent key publications - Children's Cancer Research Unit (CCRU)
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2008
Al-Oqaily A, Kennedy PJ, Catchpoole DR, Simoff SJ (2008). Comparison of Visualization Methods of Genome-wide SNP Profiles in Childhood Acute Lymphoblastic Leukaemia. In Proc. Seventh Australasian Data Mining Conference (Aus DM 2008), Glenelg, South Australia. Conference in Research and Practice in Information Technology, 87. Roddick JF, Li J, Christen P, Kennedy PJ, Eds., ACS 111 – 121.
Catchpoole DR, Guo D, Jiang H, Biesheuvel C (2008). Predicting outcome in childhood acute lymphoblastic leukaemia using gene expression profiling: Prognostication or protocol selection?. Blood 111(4):2486-2487.
Ghous H, Kennedy PJ, Catchpoole DR, Simoff SJ (2008). Kernel-based Visualisation of Genes with the Gene Ontology. In Proc. Seventh Australasian Data Mining Conference (AusDM 2008), Glenelg, South Australia. Conference in Research and Practice in Information Technology. 87. Roddick JF, Li J, Christen P, Kennedy PJ, Eds., ACS 133-140.
Gunning P, ONeill G, Hardeman E (2008). Tropomyosin-Based Regulation of the Actin Cytoskeleton in Time and Space. Physiological Reviews 88: 1-35.
Kennedy PJ, Simoff SJ, Catchpoole DR, Skillicorn DB, Ubaudi F, Al Oqaily A (2008). Integrative visual data mining to biomedical data: Investigating cases in Chronic Fatigue Syndrome and Acute Lymphoblastic Leukaemia, (Eds SJ Simoff, M Böhlen, A Mazeika), in Lecture Notes in Computer Science, Volume 4404, Visual Data Mining: Theory, Techniques and Tools for Visual Analytics., Springer, Heidelberg, 367-388.
Lau L, Stuurman K, Weitzman S (2008). Skeletal Langerhan cell histiocytosis in children: Permanent consequences and health-related quality of life in long-term survivors. Paediatric Blood and Cancer 50(3): 607-612.
Lau LMS, Nugent JK, Zhao X, Irwin MS (2008). HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function. Oncogene 27: 997-1003.
Linda Gomes, Nicole Mackie, Daniel R Catchpoole, Tony Henwood (2008). Test and Teach – In a fix about immunohistochemsitry on 60 year old tissue blocks? Journal of Histotechnology 8:125
Margetts CDE, Morris M, Astuti D, Gentle DC, Cascon A, McRonald FE, Catchpoole DR, Robledo M, Neumann HPH, Latif F, Maher ER (2008). Evaluation of a functional epigenetic approach to identify promoter region methylation in phaeochromocytoma. Endocrine-Related Cancer 15:777-786.
ONeill GM, Stehn J, Gunning PW. (2008) Tropomyosins as interpreters of the signalling environment to regulate the local cytoskeleton. Sem. Cancer Biol. 18: 35-44.
Schevzov G, ONeill GM. Tropomyosin gene expression in vivo and in vitro. In Tropomyosin, Peter Gunning, Ed. 2008, Landes Bioscience and Springer Science+Business Media.
Schevzov G, Fath T, Vrhovski B, Vlahovich N, Rajan S, Hook J, Joya JE, Lemckert F, Puttur F, Lin JJ, Hardeman EC, Wieczorek DF, ONeill GM, Gunning PW (2008). Divergent regulation of the sarcomere and the cytoskeleton. J Biol.Chem 283: 275-283.
Shehata M, Bieche I, Boutros R, Weidenhofer J, Fanayan S, Spalding L, Zeps N, Byth K, Bright RK, Lidereau R, Byrne JA (2008). Non-redundant functions for tumor protein D52-like proteins support specific targeting of TPD52. Clin. Cancer Res. 14: 5050-5060.
Shehata M, Weidenhofer J, Thamotharampillai K, Hardy JR, Byrne JA (2008). Tumor protein D52 overexpression and gene amplification in cancer- from a mosaic of microarrays. Crit. Rev. Oncogenesis 14: 33-55.
2009
Alagaratnam S, Hardy JR, Lothe RA, Skotheim RI, and Byrne JA (2009). TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours. Mol Cell Endocrinol., 306: 75-80.
Bach CT, Creed S, Zhong J, Mahmassani M, Schevzov G, Stehn J, Cowell LN, Naumanen P, Lappalainen P, Gunning PW, ONeill GM. (2009). Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol. Mar;29(6):1506-14.
Fanayan S, Shehata M, Agterof AP, McGuckin MA, Alonso MA, Byrne JA (2009). Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells. BMC Cell Biol 10: 7.
Garron M-L, Arsenieva D, Zhong J, Bloom AB, Lerner A, ONeill GM, Arold ST. (2009). Structural insights into the association between BCAR3 and Cas family members; an atypical complex implicated in anti-oestrogen resistance. J. Mol. Biol. 386(1):190-203.
Kadupitige SR, Leung KC, Sellmeier J, Sivieng J, Catchpoole DR, Bain ME, Gaëta BA (2009). MINER: Exploratory analysis of gene interaction networks by machine learning from microarray data. BMC Genomics (accepted)
Lau LMS, Wolter JK, Lau JT, Cheng LS, Smith KM, Hansford LM, Zhang L, Baruchel S, Robinson F, Irwin MS (2009). Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma. Oncogene 28: 2024-2033.
Lewis JD, Sullivan LA, Byrne JA, de Riese W, Bright RK (2009). Memory and cellular immunity induced by a DNA vaccine encoding self antigen TPD52 administered with soluble GM-CSF. Cancer Immunol. Immunother 58: 1337-49.
Luke B Hesson, Thomas L Dunwell, Wendy N Cooper, Daniel Catchpoole, Anna T Brini, Raffaella Chiaramonte, Mike Griffiths, Andrew D Chalmers, Eamonn R Maher, Farida Latif (2009). The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias. Molecular Cancer 8:42
ONeill GM (2009). The coordination between actin filaments and adhesion in mesenchymal migration. Cell Adhesion and Migration. Oct 8;3(4). [Epub ahead of print]
Taylor JG, Cheuk AT, Tsang PS, Chuug J-Y, Song YK, Desai K, Yu Y, Chen Q-R, Shah K, Mendoza A, Wei JS, Khanna C, Catchpoole DR, Qualman SJ, Hewitt SM, Merlino G, Chanock SJ, Khan J (2009). Identification of activating mutations in the receptor tyrosine kinase FGFR4 in rhabdomyosarcoma. Journal Clinical Investigations (accepted).
Thomas L Dunwell, Luke B Hesson, Tatiana Pavlova, Veronika Zabarovska, Daniel Catchpoole, Raffaella Chiaramonte, Anna T Brini, Mike Griffiths, Eamonn R Maher, Eugene Zabarovsky, Farida Latif (2009). Epigenetic analysis of childhood acute lymphoblastic leukaemia. Epigenetics 4(3):185-193.
Thomas L Dunwell, Rachel E Dickinson, Tatjana Stankovic, Ashraf Dallol, Victoria Weston, Belinda Austen, Daniel Catchpoole, Eamonn R Maher, Farida Latif (2009). Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukaemia. Epigenetics 4(4):265-269
Ubaudi F, Catchpoole DR, Guo D, Simoff SJ, Kennedy PJ (2009). Microarray data mining: selecting trustworthy genes with Gene Feature Ranking. In Data Mining for Business Applications: (Eds: Longbing Cao, Philip S Yu, Chengqi Zhang, Huaifeng Zhang), Springer, chapter 11, pages 159-168.
Wolf S, Wakelin LPG, He Z, Stewart BW, Catchpoole DR (2009). In vitro assessment of novel transcription inhibitors and topoisomerase poisons in rhabdomyosarcoma cell lines. Cancer Chemotherapy and Pharmacology 64(6) 1059-1069.
Weidenhofer J, Byrne JA (2009). Isolation of nucleic acids from hard tissues. In: Handbook of Nucleic Acid Purification. Liu D. (Ed.), Taylor & Francis CRC Press, pp. 427-448.
